Publications

  1. Kaufmann, G., Choder, M. and Groner, Y. (1980).  Synthesis of carrier-free (32P)- nucleotides triphosphates in almost quantitative yields. Anal. Biochem.  109, 98-112. 1pdf_icon_small
  2. Choder, M., Bartosin, S. and Aloni, Y. (1984).  A direct analysis of transcribed  minichromosomes: all transcribed SV40 minichromosomes have a nuclease hypersensitive region within a nucleosome-free domain.  EMBO J. 3, 2929-2936. 1pdf_icon_small
  3. Ulanovsky, L., Bodner, M. Trifonov, E.N. and Choder, M. (1986).  Curved DNA:    design synthesis and circularization.  Proc. Natl. Acad. Sci. U.S.A.  83, 862-866. 1pdf_icon_small
  4. Choder, M. and Aloni, Y. (1988).  In vitro transcribed SV40 minichromosomes, as the     bulk minichromosomes, have a low level of unconstrained negative supercoils.   Nucleic Acids Res. 16, 895-905 . 1pdf_icon_small
  5. Choder, M. and Aloni, Y. (1988).  RNA polymerase II allows unwinding and rewinding of the DNA and thus maintains a constant length of the transcription bubble.  J. Biol. Chem263, 12994-13002. 1pdf_icon_small
  6. Resnikov, O., Ben-Asher, E., Bengal, E., Choder, M., Hay, N., Kessler, M., Ragimov, N., Seiberg, M., Skolnik-David, H. and Aloni, Y. (1988).  Transcription termination in animal viruses and cells. Gene 72, 91-104 . 1pdf_icon_small
  7. Balzi, E., Choder, M., Chen, W., Varshavsky, A. and Goffeau, A. (1990). Cloning and functional analysis of the Arginyl-tRNA-protein transferase gene ATE1 of Saccharomyces cerevisiae.  J. Biol. Chem265, 7464-7471 . 1pdf_icon_small
  8. Chen, W., Balzi, E., Capieaux, E., Choder, M. and Goffeau A. (1991). DNA sequencing of a 17 kb Hind III fragment spanning the LEU1 and ATE1 loci on chromosome VII from Saccharomyces cerevisiaeYeast, 7, 287-299. 1pdf_icon_small
  9. Choder, M. (1991). A general topoisomerase I-dependent transcriptional repression in the stationary-phase in yeast. Genes & Dev. 5,2315-2326. 1pdf_icon_small
  10. Choder, M. (1993).  A growth limiting mechanism in the last growth phase of the yeast life cycle involves RPB4, a subunit of RNA polymerase II.  J. Bacteriol. 175, 6358-6363. 1pdf_icon_small
  11. Choder, M. and Young, R. A. (1993).  A portion of RNA polymerase II molecules has a component essential for stress responses and stress survival. Mol. Cell. Biol. 13, 6984-6991. 1pdf_icon_small
  12. Weisman, R. Choder, M., and Koltin Y. (1997).  Rapamycin specifically interferes with the developmental response of fission yeast to starvation.  J. Bacteriol. 179, 6325-6334. 1pdf_icon_small
  13. Rosenheck, S., and Choder, M. (1998).  Rpb4, a subunit of RNA polymerase II, enables the enzyme to transcribe at temperature extremes in vitroJ. Bacteriol. 180,       6187-6192. 1pdf_icon_small
  14. Shefer, A., Varon, M., and Choder, M. (1999).  Rpb7 can interact with RNA polymerase II and support transcription during some stresses independently of Rpb4.  Mol. Cell. Biol. 19, 2672-2680. 1pdf_icon_small
  15. Meunier, J-R., and Choder, M. (1999).  Saccharomyces cerevisiae colony growth and ageing: biphasic growth accompanied by changes in gene expression and colony morphology.  Yeast, 15, 1159-1170. 1pdf_icon_small
  16. Paz, I. Abramovitz, L., and Choder, M. (1999).  Starved Saccharomyces cerevisiae cells have the capacity to support internal initiation of translation.  J. Biol. Chem274,  21741-21745. 1pdf_icon_small
  17. Paz, I., Meunier, J-R., and Choder, M. (1999).  Monitoring dynamics of gene expression in yeast during stationary phase.  Gene,  236, 33-42. 1pdf_icon_small
  18. Jona, G.,  Choder, M., and Gileadi, O. (2000) Glucose starvation induces a drastic reduction in the rates of both transcription and degradation of mRNA in yeast.  Biochem. Biophys. Acta 1491, 37-48. 1pdf_icon_small
  19. Varon, M., and Choder, M. (2000). Organization and cell-cell interaction in starved Saccharomyces cerevisiae colonies.  J. Bacteriol.182, 3877-3880.                  A photograph from this paper is presented as a cover picture.  1pdf_icon_small
  20. Weisman, R., and Choder, M. (2001). The S. pombe TOR homologue, tor1+, is required for sexual development, entrance into stationary phase and responses to stress conditions.  J. Biol. Chem276, 7027-7032. 1pdf_icon_small
  21. Weizman, R., Finkelstein, S. and Choder, M. (2001). Rapamycin blocks sexual development in fission yeast through inhibition of FKBP12 homolog. J. Biol. Chem276, 24736-24742 1pdf_icon_small
  22. Paz, I. and Choder, M. (2001).  Eukaryotic translation initiation factor 4E-dependent translation is not essential for survival of starved yeast cells.      J. Bacteriol183, 4477-4483. 1pdf_icon_small
  23. Farago, M., Nahari, T., Hammel, C., Cole, C. N., and Choder, M. (2003).   Rpb4p, a Subunit of RNA Polymerase II, Mediates mRNA Export during Stress.  Mol. Biol. Cell 14, 2744-2755. 1pdf_icon_small
  24. Lotan, R, Goler Bar-On, V., Harel-Sharvit, L., Duek, L., Melamed, D., and Choder, M.  (2005). The RNA polymerase II subunit Rpb4p mediates decay of a specific class of mRNAs. Genes & Dev. 19, 3004-3016. 1pdf_icon_small
  25.  Topaz, O., Indelman, M., Chefetz, I., Geiger, D., Metzker, A., Altschuler, Y., Choder, M., Bercovich, D., Uitto, J., Bergman, R., Richard, G., and Sprecher, E. (2006). A Deleterious Mutation in SAMD9 causes Normophosphatemic Familial Tumoral Calcinosis. American Journal of Human Genetics 79, 759-764. 1pdf_icon_small
  26. Selitrennik, M., Duek, L, Lotan, R., and Choder, M. (2006).  Nucleo-cytoplasmic shuttling of Rpb4 and Rpb7 subunits of yeast RNA polymerase II by two pathways. Eukaryotic Cell  5, 2092-2103. 1pdf_icon_small
  27. Dori, D. and Choder, M. (2007).  Conceptual modeling of biological systems: the mRNA lifecycle as a case in point. PLoS One2,e872. 1pdf_icon_small
  28. Lotan, R., Goler Bar-On, V., Duek, L., Haimovitz, G., and Choder, M. (2007).  The Rpb7p subunit of yeast RNA polymerase II plays roles in the two major cytoplasmic mRNA decay mechanisms. J. Cell Biol. 178, 1133-1143. 1pdf_icon_small
  1. Mandel, H., Shemer, R., Zvi U. Borochowitz, Z. U., Okopnik, M., Knopf, C., Indelman, M., Drugan, A., Dov Tiosano, D., Gershoni, R.,Choder, M., and Sprecher, E.  (2008). Female sex reversal with dysgenesis of kidneys, adrenals and lungs (SERKAL syndrome): a novel autosomal recessive disorder caused by ahomozygous loss-of-function mutation in WNT4.  American Journal of Human Genetics 82, 39-47.
  2.  Nousbeck, J. Spiegel, R., Ishida-Yamamoto, A., Indelman, M., Shani-Adir, A., Adir, N.,  Lipkin, E.,  Bercovici, S.,  Geiger, D.,  van Steensel, M. A. Steijlen, P. M.,. Bergman, R., Bindereif, A., Choder, M., Shalev, S.  Sprecher, E.  (2008).  Alopecia, Neurological defects and Endocrinopathy (ANE) syndrome caused by decreased expression of RBM28, a nucleolar protein associated with ribosome biogenesis.  American Journal of Human Genetics 82, 1114-21.
  3. Goler-Baron, V., Seletrinnik, M., Barkai, O., Haimovitz, G., Lotan, R., and Choder, M.  (2008). Transcription in the nucleus and mRNA decay in the cytoplasm are coupled processes. Genes & Dev.22, 2022-2027. 1pdf_icon_small
  4. Wasserman TKatsenelson KDaniliuc SHasin TChoder, M., and Aronheim A. (2010). A novel c-Jun N-terminal kinase (JNK)-binding protein WDR62 is recruited to stress granules and mediates a nonclassical JNK activation. Mol. Biol. Cell21,117-30.
  5.  Harel-Sharvit, L., Eldad, N., Haimovich, G., Barkai, O., Duek, L. and Choder, M. (2010). RNA polymerase II subunits link transcription and mRNA decay to translation.   Cell 143, 552-563. 1pdf_icon_small
  1.   Choder, M. (2011). mRNA imprinting: additional level in the regulation of gene  expression. Cellular Logistics 1, 37-40. 1pdf_icon_small
  2.  Shalem, O., Groisman, B., Choder, M., Dahan O., and Pilpel, Y. (2011) Transcriptome Kinetics Is Governed by a Genome-Wide Coupling of mRNA Production and Degradation: A Role for RNA Pol II. PLoS Genet 7(9): e1002273. 1pdf_icon_small
  3.  Bregman, A., Avraham-Kelbert, M., Barkai, O., Duek, L., Guterman, A., and   Choder, M. Promoter elements regulate cytoplasmic mRNA decay. (2011).   Cell147, 1473-83. 1pdf_icon_small
  1. Somech, Y., Choder, M., and Dori, D. Conceptual Model-Based Systems Biology: Mapping Knowledge and Discovering Gaps in the mRNA Transcription Cycle. PLoS One 7, e51430. 1pdf_icon_small
  2. Haimovich, G., Medina, A.D., Causse, S.Z., Garber, M., Millán-Zambrano, G., Barkai, O., Chávez, S., Pérez-Ortín, J.E., Darzacq, X., and Choder, M. (2013). Gene expression is a circular: factors for mRNA degradation also foster mRNA synthesis. Cell, 153, 1000-1011. 1pdf_icon_small

 Reviews

  1. Choder, M. (2004).  Rpb4 and Rpb7: subunits of RNA polymerase II and  beyond. Trends Biochem Sci. (TiBS29, 674-681. 1pdf_icon_small
  2. Dahan, N. and Choder, M. (2013). The transcriptional machinery regulates mRNA translation and decay in the cytoplasm.  In BBA special issue entitled The biochemistry and structural biology of RNA polymerase II transcript elongation, Edited by Svejstrup, JQ. BBA 1829, 169-173.  1pdf_icon_small
  3. Haimovich, G., Choder, M. Singer R., and Trcek, T. The linkage between mRNA synthesis and decay. In BBA Special issue on “RNA decay mechanisms”. In press. 1pdf_icon_small
  4. Perez-Ortin, J.E., Alepuz, P., Chavez, S., and Choder, M. Regulation of eukaryotic gene expression by mRNA decay. Solicited by J. Mol. Biol. For a special issue on “Non-coding RNA in Systems”. In press. 1pdf_icon_small