Papers dealing with mRNA coordinators
- The mRNA coordination idea was first discussed in our paper Harel-Sharvit et al. 2010.
- Selected for the Journal "Leading Edge Preview" Cell 143, 501-502.
- Selected for "Research Highlight" in Nature Reviews Nat. Rev. Mol Cell Biol. 12, 8
- The possible languish used by mRNA coordinators Rpb4/7 Richard et al 2021
The mRNA coordination idea was first discussed in our paper Harel-Sharvit et al. 2010. See the section “Rpb4/7 Coordinates the mRNA Lifecycle” in the Discussion of this paper.
Rpb4/7 mediates mRNA synthesis, transport, translation, and decay through ‘‘mRNA imprinting.’’ It undergoes more than 100 possible combinations of posttranslational modifications that change temporally and spatially. These modifications seem to represent a language by which the above stages of the mRNA life cycle communicate.