“mRNA coordinator” concept

 

Papers dealing with mRNA coordinators

 

 

 

 

“mRNA coordinator” concept

The mRNA coordination idea was first discussed in our paper Harel-Sharvit et al. 2010. See the section “Rpb4/7 Coordinates the mRNA Lifecycle” in the Discussion of this paper.

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Rpb4/7 mediates mRNA synthesis, transport, translation, and decay through ‘‘mRNA imprinting.” See also.  It undergoes more than 100 possible combinations of posttranslational modifications that change temporally and spatially. These modifications seem to represent a language by which the above stages of the mRNA life cycle  communicate.